Frequently Asked Questions - Ultra-Thin

The main advantage ultra-thin section microscopy has over any other type of service is that cells and tissues can be examined at an ultrastructural level. This technique provides details of the interior of the cells and tissues, including organelle structure, morphology of macromolecules, such as virus particles, and does so without causing distortion of the cells or tissues.

Contact ABI and speak with a technical support representative to learn if ultra-thin section electron microscopy is appropriate for your needs.

ABI will provide you with an appropriate aldehyde-based fixative, depending on the type of sample you are working with, along with a washing buffer and a protocol for sample fixation. ABI will send you this material free of charge.

Ultra-thin sectioning reveals fine details of cell and tissue ultrastructure as well as the structure of viruses or other present microbes.  Cells or tissues embedded in plastic are thin sectioned, mounted and stained, and examined by transmission electron microscopy.