13-138-100

Name: 
HHV-6A Early Protein p41/38
Technical Data
Size: 
100 µg
Protein Concentration: 
[varies by lot] mg/ml determined by Bradford Assay using Bovine Gamma Globulin as the standard.
Presentation: 
Purified IgG in phosphate buffer saline (pH 7.2) with 0.01% Thimerosal
Isotype: 
IgG1
Purity: 
> 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.
Functional Activity: 
This monoclonal antibody derived from hybridoma cell-line induced ascites fluid, originally reactive with both HHV-6A and B, but following in vitro and in vivo passages, now reacts only with HHV-6 AGS,U1102 by IFA.  Does not cross-react with HHV-6BZ-29. HSB-2 cells infected with HHV-6A  that reacted with this antibody display patchy intranuclear fluorescence by IFA.
Recommended Use: 
HHV-6A p41/38 MAb, if used in conjunction with HHV-6 A/B MAb to early phosphoprotein p41 (ABI Cat No. 13-216-100), can differentially identify types A or B of HHV-6 isolates and also be used to detect early viral protein expression in infected cells, indicating active virus replication. These MAbs can be used in IFA and/or IHC detection systems.
Storage Temperature: 
-20°C

Mouse MAb to the early protein, p41/38 of HHV-6A originating from ascites fluid and purified by protein G affinity chromatography. This MAb is used in conjunction with HHV-6 A/B MAb to early phosphoprotein p41, can differentially identify HHV-6 variant A or variant B isolates and can be used to detect early viral protein expression in infected cells, indicating active virus replication. This MAb can be used in immunofluorescence and/or immunohistochemistry detection system. Does not cross react with HHV-6B.

MSDS: 
300-013.MSDS