HHV-6A Early Protein p41/38

in
Catalog Number: 
13-138-100
Status: 
Current product--usually ships within 2 business days
Discount: 
Quantity discounts are available for quantities of 5 or more. Please contact us for details.
Size: 
100 µg
Use: 
For research use only. Not for use in diagnostic procedures.
Storage Temperature: 
-20˚C

Product Description: Mouse monoclonal antibody to the early protein, p41/38 of HHV-6A. This antibody originates from ascites fluid and is purified by protein G affinity chromatography

Hybridoma Clone: C 5

Protein Concentration: [varies by lot] mg/mL determined by BCA Assay. Alternative methods for determining protein concentration may give different results.

Presentation: Purified IgG in phosphate buffer saline (pH 7.2) with 0.01% Thimerosal

Isotype: IgG1

Purity: > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

IFA Titer:

  1. HHV-6AGS infected HSB-2 cells = Reactive (IFA Titer: 1:80-1:160)
  2. HHV-6BZ-29 infected Molt-3 cells = Non-reactive

 

Functional Activity: This monoclonal antibody derived from hybridoma cell-line induced ascites fluid, originally reactive with both HHV-6A and B, but following in vitro and in vivo passages, now reacts only with HHV-6AGS,U1102 by IFA.  Does not cross-react with HHV-6BZ-29. HSB-2 cells infected with HHV-6A  that reacted with this antibody display patchy intranuclear fluorescence by IFA.

Recommended Use: HHV-6A p41/38 MAb, if used in conjunction with HHV-6 A/B MAb to early phosphoprotein p41 (ABI Cat No. 13-216-100), can differentially identify types A or B of HHV-6 isolates and also be used to detect early viral protein expression in infected cells, indicating active virus replication. These MAbs can be used in IFA and/or IHC detection systems.

Shipping and Storage: 
This product is shipped frozen on dry ice. Store at -20°C upon receipt. Avoid multiple freeze-thaw cycles as product degradation may result.
Documents
MSDS: 
300-013.MSDS