HHV-6A Early Protein p41/38 (cell culture supernatant)
Product Description: Mouse monoclonal antibody to the early protein, p41/38 of HHV-6A. This antibody originates from hybridoma cell culture supernatant and is concentrated by ultrafiltration.
Hybridoma Clone: C 5
Protein Concentration: [varies by lot] mg/mL determined by BCA Assay. Alternative methods for determining protein concentration may give different results.
Presentation: Concentrated hybridoma cell culture supernatant with 0.01% Thimerosal.
Isotype: IgG1
IFA Titer: HHV-6AGS infected HSB-2 cells: 1:32-1:64 (Greater than or equal to 2+ intensity using FITC-conjugated goat anti-mouse IgG (H+L) as secondary antibody).
Functional Activity: This antibody derived from hybridoma cell culture supernatant was originally reactive with both HHV-6 A and B, but following in vitro passages, the antibody now reacts only with HHV-6 AGS,U1102 by IFA. Does not cross react with HHV-6BZ-29. HSB-2 cells infected with HHV-6A that reacted with this antibody display patchy intranuclear fluorescence in IFA.
Recommended Use: HHV-6A p41/38 MAb, if used in conjunction with HHV-6A/B MAb to early phosphoprotein p41 (ABI Cat. No. 13-216-100), can differentially identify types A or B of HHV-6 isolates and also be used to detect early viral protein expression in infected cells, indicating active virus replication. These MAbs can be used in IFA and/or IHC detection systems.
*Note: Upon thawing, centrifuge the vial for a few seconds to remove residual droplets from the lid.


