KSHV/HHV-8 MAb to ORF K8.1 A/B
Product Description: Mouse monoclonal antibody to HHV-8 virion-associated envelope glycoprotein, a late protein encoded by ORF K 8.1 A and K 8.1 B (K 8.1 A/B). Fusion proteins expressed in bacteria were 52-54 kDa and 48-50 kDa by ORF K 8.1 A and ORF K 8.1 B, respectively. This antibody originates from serum-free hybridoma cell culture medium and is purified by protein G agarose affinity chromatography.
Hybridoma Clone: 4A4
Protein Concentration: [varies by lot] mg/mL determined by BCA Assay. Alternative methods for determining protein concentration may give different results.
Fill Volume: Varies by lot.
Presentation: Purified IgG supplied in PBS, pH 7.4 containing 0.1% sodium azide.
Isotype: IgG1
Purity: > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE
IFA Titer: Varies by lot
Functional Reactivity: Reactive with lytic cycle-associated late envelope glycoprotein (ORF K 8.1 A/B) of HHV-8. Reactive in IFA, ELISA, RIP, Western blot, and in Immune Electron Microscopy assay. In IFA, this MAb shows bright fluorescence predominantly localized in the cytoplasm and plasma membranes. No reactivity with EBV-positive (P3HR-1) or HHV-8 negative (BJAB) cells.


