HHV-6A/B MAb to gp116/64/54

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Catalog Number: 
13-218-100
Status: 
Current product--usually ships within 2 business days
Discount: 
Quantity discounts are available for quantities of 5 or more. Please contact us for details.
Size: 
100 µg
Use: 
For research use only. Not for use in diagnostic procedures.
Storage Temperature: 
-20˚C

Product Description: Mouse monoclonal antibody to glycoprotein gp116/64/54 of HHV-6A and B. This antibody originates from mouse ascites fluids and is purified by protein G chromatography.

Hybridoma Clone: 6A5G3

Protein Concentration: Determined by BCA Assay using Bovine Gamma Globulin (BGG) as the standard. Alternative methods for determining protein concentration may give different results.

Presentation: Purified IgG supplied in PBS, pH 7.4 containing 0.1% Thimerosal.

Isotype: IgG2b

Purity: > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE gel.

IFA Titer: 1:40 - 1:80 (>/= 2+ intensity)

Functional Activity: Immunoreactive with HHV-6A and B glycoprotein gp116/gp64/gp54 in infected cell cultures, PBMCs and tissues. In IFA with HHV-6A and B infected cells, this MAb shows membrane or cytoplasmic fluorescence depending on the stage of infection1. Recognizes HHV-6A and B specific viral proteins by immunoprecipitation2,3. Reactive in immunohistochemistry4 on formalin-fixed paraffin-embedded tissue sections of oral carcinoma5 and multiple sclerosis brain tissue specimens.

  1. 1. Ablashi D, Balachandran N, Josephs SF, et al. "Genomic polymorphism, growth properties, and immunologic variations in human herpesvirus-6 isolates." Virology. 1991;184(2):545-552.
  2. 2. Balachandran N, Amelse RE, Zhou WW, Chang CK. "Identification of proteins specific for human herpesvirus 6-infected human T cells." J. Virol.. 1989;63:2835-2840.
  3. 3. Chandran B, Tirawatnapong S, Pfeiffer B, Ablashi D. "Antigenic relationships among human herpesvirus-6 isolates." Journal of Medical Virology. 1992;37(4):247-254.
  4. 4. Citekey 163 not found
  5. 5. Citekey 164 not found
Shipping and Storage: 
This product is shipped frozen on dry ice. Store at -20°C upon receipt. Avoid multiple freeze-thaw cycles as product degradation may result.
Documents
MSDS: 
300-013.MSDS